In the USA, data on macrolide consumption showed a decreasing trend over the past 10 years, but also with a clear predominance of azithromycin as the most prescribed drug (190 and 90 macrolide prescriptions per 1000 persons and 170 and 86 azithromycin prescriptions per 1000 persons in 2011 and 2021, respectively) [ 204 , 205 ].
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An Overview of Macrolide Resistance in Streptococci: Prevalence, Mobile Elements and Dynamics.
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