Enhanced Permeability and Retention Effect as a Ubiquitous and Epoch-Making Phenomenon for the Selective Drug Targeting of Solid Tumors.

J Pers Med · 2022 · PMC9784116 · PMID 36556185

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extremely significantno p-value reported

This finding was extremely significant because at the same time they had been working with the antitumor agent neocarzinostatin (NCS) (12 kDa) to determine how to deliver NCS to cancer tissues as well as metastatic cancers in vivo [ 3 ].

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