Barely Significant
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The Association of Biochemical and Genetic Biomarkers in VEGF Pathway with Depression.

Pharmaceutics · 2022 · PMC9785844 · PMID 36559251

3
hedged sentences
0.0760
closest p · 1.5× alpha
0.0760
boldest claim

The sentences

close to significancep -value = 0.076so close (0.05 < p ≤ 0.1)
Table 2 shows that after multivariate linear regression the association of the VEGF rs699947 polymorphism with the number of suicide attempts in the recessive model was close to significance ( Table 2 ; p -value = 0.076).

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very close to significancep = 0.076so close (0.05 < p ≤ 0.1)
While this was very exciting, we have not found any association with depression risk, although suicide ideation was very close to significance in the multivariate model (variant genotypes β: +0.45, p = 0.076; Table 2 ), and it showed a p < 0.05 regarding the number of suicide attempts (AA carriers with almost double the suicide attempts; Figure S2R ).

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reached near significanceno p-value reported
Multivariate models confirmed the lack of association between biochemical data with symptoms, although in some cases, p -values reached near significance ( Tables S4–S7 ). 3.5.

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