Safety and Tolerability of an Antimalarial Herbal Remedy in Healthy Volunteers: An Open-Label, Single-Arm, Dose-Escalation Study on <i>Maytenus senegalensis</i> in Tanzania.

Trop Med Infect Dis · 2022 · PMC9787516 · PMID 36548651

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a decreasing trendno p-value reported

Furthermore, there was a decreasing trend in the mean value of total bilirubin from the baseline for groups 3 and 4.

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an increasing trendno p-value reported

In this study, there was an increasing trend in mean values of the ALT parameter for the study group that received the highest dose of the tested product up to day seven after administration, and then it started to return to baseline.

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