Mutation in the CCAL1 locus accounts for bidirectional process of human subchondral bone turnover and cartilage mineralization.

Rheumatology (Oxford) · 2022 · PMC9788812 · PMID 35412619

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highly significantno p-value reported

Notably, lower expression of MGP was highly significant, which was also observed in neo-cartilage deposited by primary chondrocytes with OPG-XL ( Fig. 1F ).

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