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Epidemiological trends of hand osteoarthritis from 1990 to 2019: Estimates from the 2019 Global Burden of Disease study.

Front Med (Lausanne) · 2022 · PMC9790907 · PMID 36579153

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a slightly increasing trendno p-value reported
However, a slightly increasing trend was observed in the other three regions ( Table 1 ).

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a decreasing trendno p-value reported
an increasing trendno p-value reported
Regarding the findings in GBD regions and countries, the ASIR of hand OA exhibited an increasing trend in 88 countries and 12 regions, a decreasing trend in 75 countries and three regions, and remained unchanged in 29 countries and six regions.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.