Altered type I collagen networking in osteoporotic human femoral head revealed by histomorphometric and Fourier transform infrared imaging correlated analyses.

All the band area ratios displayed a decreasing trend: 1340/1160 (collagen's proline), 1320/1160 (a‐helices), 1240/1160 (triple helices), and 1204/1160 (amino acids' lateral chains) showed statistically comparable values for H and OP+ samples, within cortical and trabecular regions, while a significant decrease was found in OP– spectra; as regards 1284/1160 (triple helices) band area ratio, a significant decrease was found in OP+ and, as a further extent, in OP– spectra.

also in 47,180 other papers