Barely Significant
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Investigation of buprenorphine-related deaths using urinary metabolite concentrations.

Drug Test Anal · 2022 · PMC9796430 · PMID 35834288

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a decreasing trendno p-value reported
An investigation on drug residues in used syringes in Helsinki (Finland) revealed that the proportion of syringes containing naloxone changed from 11% in 2017 to 8% in 2018 and further to 5% in 2019, showing a decreasing trend. 16 A survey by Fältberg et al. 37 asking about participants' substance abuse at four time‐points between 2008 and 2018 in South‐Western Finland found that 66–81% of respondents had abused buprenorphine–naloxone during the last 6 months.

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