The expression of hippocampal GluN2A in the CUMS group showed an increasing trend, and the expression of GluN2A in the hippocampus in the isorhynchophylline group was significantly lower than that of the CUMS group (one-way ANOVA followed by Dunnett’s tests; F 2 , 12 = 3.664, P = 0.057; CUMS vs. control: P = 0.171; Iso vs.
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Isorhynchophylline ameliorates stress-induced emotional disorder and cognitive impairment with modulation of NMDA receptors.
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