Publication bias in pharmacogenetics of adverse reaction to antiseizure drugs: An umbrella review and a meta-epidemiological study.

PLoS One · 2022 · PMC9803138 · PMID 36584134

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highly significantno p-value reported

In contrast, the association between the genetic variant HLA-A*31:01 and the risk of SJS in people treated with carbamazepine seems to be underestimated by a factor two when taking into account a potential publication bias (OR NP of 6 versus OR TM of 12), surprisingly suggesting potential highly significant unpublished clinical studies.

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