Evidence of shared transcriptomic dysregulation of HNRNPU-related disorder between human organoids and embryonic mice.

iScience · 2023 · PMC9804147 · PMID 36594023

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

borderline significancep< 0.06so close (0.05 < p ≤ 0.1)

Similarly, GABAergic and SCPN populations were enriched in one mutant line with corresponding borderline significance (p< 0.06) in the second mutant clone.

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highly significantno p-value reported

We found highly significant enrichment in genes both similarly upregulated and similarly downregulated, without any enrichment of genes dysregulated in opposing directions ( Figures 3 C and 3D; Table S3 ).

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