Differential dose responses of transcranial focused ultrasound at brain regions indicate causal interactions.

Brain Stimul · 2022 · PMC9806861 · PMID 36496128

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a decreasing trendno p-value reported

Lower FUS pulse intensities elicited BOLD signal changes in a decreasing trend at the target area 3a/3b (high-medium-low: 0.46%, 0.25%, and 0.19%) and in varying degrees at off-target area 1/2 (0.46%, 0.29%, 0.15%), S2 (0.45%, 0.36%, 0.15%), MCC (0.35%, 0.34%, 0.18%), VPL (0.26%, 0.24%, 0.18%), MD (0.04%, 0.002%, 0.009%), auditory cortex (0.17%, 0.015%, 0.015%), and Insula (0.36%, 0.08%, 0.13%) ( Fig. 3C ).

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