Effect of sleep loss on pain-New conceptual and mechanistic avenues.

Front Neurosci · 2022 · PMC9807925 · PMID 36605555

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Nine and twelve hours of sleep deprivation caused an increased sensitivity for noxious heat (hotplate set at 52 C, radiant heat with Hargreaves), pressure (von Frey filaments) and sustained pain (capsaicin), with an overall trend toward higher responses in females (Page et al., 2014 ; Vanini et al., 2014 ; Vanini, 2016 ; Alexandre et al., 2017 ; Hambrecht-Wiedbusch et al., 2017 ).

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