A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia.

Nat Immunol · 2023 · PMC9810535 · PMID 36522544

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highly significantno p-value reported

Comparison of gene expression in individual MECOM -high AML cell lines to the average expression in MECOM -low AML lines revealed highly significant MECOM network enrichment in MUTZ-3, F36P, HNT34 and OCI-AML4 cells (Extended Data Fig. 8b ).

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