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Prevalence and Etiological Profile of Hypercalcemia in Hospitalized Adult Patients and Association with Mortality.

Indian J Endocrinol Metab · 2022 · PMC9815194 · PMID 36618516

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an increasing trendno p-value reported
Vitamin D intoxication is fast becoming one of the important causes of hypercalcemia.[ 4 ] Various studies conducted in India have demonstrated the rising trend of Vitamin D intoxication in the masses, primarily because of unsupervised usage of Vitamin D supplements, especially parenteral preparations.[ 17 ] The above-referenced study from North India did report a relatively high prevalence of Vitamin D intoxication ( n = 21, 5.5%).[ 2 ] Another study from North India reported an increasing trend for hypervitaminosis D from 1.48% to 7.82% over 6 years from 2011 to 2016.[ 18 ] Yet another case series from the Northern part of India had collated 16 cases of Vitamin D intoxication; the median (range) serum 25-hydroxyvitamin D level was 371 (175–1161) ng/ml.[ 6 ] We also observed a high prevalence of patients with Vitamin D intoxication (8.7%), all of whom had a history of multiple intramuscular injections in the recent past.

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