In addition, we found that genotypes of the IL-1 gene cluster SNPs are associated with a higher production of the relative cytokines; in particular IL-1A rs1800587TT might be significant a risk factor for sepsis, septic shock and neurological symptoms.
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IL-1 Superfamily Member (<i>IL-1A</i>, <i>IL-1B</i> and <i>IL-18</i>) Genetic Variants Influence Susceptibility and Clinical Course of Mediterranean Spotter Fever.
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