The functional annotation of the top leading-edge genes showed highly significant enrichment of categories related to the regulation of cell differentiation, canonical Wnt signaling, cell development and maturation, and regulation of epithelial cell differentiation ( Figure 5 B). 3.4.
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Transcriptomic Changes Associated with <i>ERBB2</i> Overexpression in Colorectal Cancer Implicate a Potential Role of the Wnt Signaling Pathway in Tumorigenesis.
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