Barely Significant
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The Association between Baseline Proton Pump Inhibitors, Immune Checkpoint Inhibitors, and Chemotherapy: A Systematic Review with Network Meta-Analysis.

Cancers (Basel) · 2022 · PMC9818995 · PMID 36612290

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marginally significantno p-value reported
Pairwise Meta-Analysis for Chemotherapy Cohorts ( Supplementary Results 9 ) The use of PPIs is associated with a significant 12% higher all-cause mortality in patients with advanced NSCLC receiving chemotherapy, with a marginally significant higher progression rate ( Supplementary Figures S35 and S36 ).

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