Pathogenic tau-induced transposable element-derived dsRNA drives neuroinflammation.

Our findings were nevertheless highly significant and consistent with consequences of genetic manipulation of Su(var)205 and Su(var)3-9 .

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We detect an overall trend toward increased retrotransposon-derived dsRNA in tau transgenic Drosophila , with a modest but statistically significant increase in 1731{}2219 and Het-A{}6270 , alongside a robust elevation of Tabor{}77 ( Fig. 5, A and B , and fig.

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