Design of κ-Opioid Receptor Agonists for the Development of Potential Treatments of Pain with Reduced Side Effects.

Molecules · 2023 · PMC9822356 · PMID 36615540

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a decreasing trendno p-value reported

In vitro binding studies showed good KOR affinity and potency, but weak selectivity with a decreasing trend as the number of carbons increased [ 27 ].

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