Consideration of patient age of symptom onset showed a nonsignificant trend toward the latest disease onset for the ALS-Glia subtype (63.2 ± 1.83 years; presented as mean ± standard error) and earliest disease onset for the ALS-Ox subtype (60.4 ± 1.16 years; Fig. 5b , Table S1 ).
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Molecular subtypes of ALS are associated with differences in patient prognosis.
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