Compared with Rspo3 inv ;MMTV‐ Wnt1 mice that overexpress the Wnt1 transgene only ( n = 49), there was no significant difference in tumor‐free survival ( p = 0.06), despite a slight trend towards reduced survival (Figure 5A ).
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R-spondin-3 is an oncogenic driver of poorly differentiated invasive breast cancer.
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