highly significantp-value = 5.41e-11
The protein-protein interaction network comprised of 44 nodes and 49 edges at an average node degree of 2.23 with a highly significant interaction enrichment (p-value = 5.41e-11), indicating that these proteins form at least a partially connected biological group. 3.5 Zebrafish functional validation The TF genes DACH1, WT1 , and LMX1B , which were downregulated in DN based on our DEG analysis, are master regulators of gene expression in podocyte differentiation.