Changes of Klebsiella pneumoniae infection and carbapenem resistance in ICU elderly infected patients before and after the COVID-19 pandemic in Zhengzhou, China.

catarrhalis) infections among children in Zhengzhou, China showed a decreasing trend during the COVID-19 pandemic. 1 , 2 , 3 Previous studies also reported changes in carbapenemase-producing Enterobacteriaceae and extended-spectrum beta-lactamase (ESBL) E. coli infections during the COVID-19 pandemic. 4 , 5 However, Klebsiella pneumoniae ( K. pneumoniae ), especially carbapenem-resistance K. pneumonia (CRKP) infection, is the main cause of mortality among elderly in the ICU, and its’ impact during the COVID-19 pandemic has not been reported.

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Importantly, the number of infections showed a decreasing trend before and after the COVID-19 pandemic, particularly in the >80 years age group, but the percentage of positive cases showed an increasing trend in the elderly, especially, in the >80 years age group.

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