Associations of the APOE ε2 and ε4 alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer's disease biomarkers.

Aging (Albany NY) · 2022 · PMC9831745 · PMID 36399096

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highly significantno p-value reported

By showing the robust and highly significant associations of the ε4 allele with CSF tau, our analysis supports previous findings on the connections between the ε4 allele and tau aggregation [ 17 , 33 , 34 ].

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