Safety and Tolerability of Nicotinamide Riboside in Heart Failure With Reduced Ejection Fraction.

JACC Basic Transl Sci · 2022 · PMC9831861 · PMID 36644285

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an increasing trendno p-value reported

During the titration period, trough NR levels were generally higher in participants randomized to NR than those randomized to placebo; however, levels in the NR participants were quite variable over time and did not show an increasing trend corresponding to the escalation in dose ( Figure 3C ).

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