Barely Significant
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pIChemiSt ─ Free Tool for the Calculation of Isoelectric Points of Modified Peptides.

J Chem Inf Model · 2023 · PMC9832473 · PMID 36573842

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The sentences

might be significantno p-value reported
The capping allows modeling the effect of peptide backbone on predicted p K a values of side chains, which might be significant as the carbonyl groups have strong electron-withdrawing character.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.