X-linked inhibitor of apoptosis protein represents a promising therapeutic target for relapsed/refractory ALL.

EMBO Mol Med · 2023 · PMC9832863 · PMID 36416169

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0.1000

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borderline significanceP < 0.1so close (0.05 < p ≤ 0.1)

Cells with strong XIAP KD differed from cells with moderate XIAP KD and sh‐CTRL regarding several GO‐terms on apoptosis signaling, although at borderline significance ( P < 0.1, Table EV2 ), pinpointing towards apoptosis as underlying mechanism for cell death by strong XIAP KD.

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