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Social burden of three major diseases in Japan: A time trend and future projections using the comprehensive cost of illness method.

PLoS One · 2023 · PMC9833557 · PMID 36630469

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a decreasing trendno p-value reported
However, in future projections, it was estimated that the total C-COI of cancer will show a decreasing trend from 2020 onwards.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.