Microdeletions and microduplications linked to severe congenital disorders in infertile men.

Sci Rep · 2023 · PMC9834233 · PMID 36631630

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highly significantno p-value reported

A highly significant enrichment of the LRRC69 deletion among cases with SPGF compared to population-based participants in the Estonian biobank (EstBB) 27 , 28 was observed (7/215 vs. 386/45,390; 3.3% vs. 0.85%; χ 2 test, OR = 3.9 [95%CI 1.8–8.4], P = 0.0001; Fig. 2 c, Supplementary Table S6 ).

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