Altered circulating GDF-15 level predicts sex hormone imbalance in males with major depressive disorder.

BMC Psychiatry · 2023 · PMC9835386 · PMID 36635686

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closely significantlyno p-value reported

These previous investigations confirm our results that T/E ratio was closely significantly and negatively associated with circulating GDF15 level in depressed patients.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.