TIMP-1 is a novel ligand of Amyloid Precursor Protein and triggers a proinflammatory phenotype in human monocytes.

J Cell Biol · 2023 · PMC9837626 · PMID 36629908

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highly significantno p-value reported

A link between TIMP-1 and monocyte activation in patients was further corroborated by a highly significant positive correlation of TIMP-1 expression with the previously defined TICS panel ( Fig. 3 C ) in a broad variety of tumor diseases.

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