highly significantp < 0.001
The overall relationship across voxels is highly significant (Pearson correlation, r = −0.57; p < 0.001; Fig. 4 B , C , purple) after using a permutation test with Moran spectral randomization to comprehensively account for spatial autocorrelation in the maps ( Wagner and Dray, 2015 ; Vos de Wael et al., 2020 ).