A conditional <i>Smg6</i> mutant mouse model reveals circadian clock regulation through the nonsense-mediated mRNA decay pathway.

Sci Adv · 2023 · PMC9839329 · PMID 36638184

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7J ); when normalizing mRNA amplitudes for pre-mRNA fold changes, as a means to control for differences in transcriptional rhythmicity at the locus, the decrease in rhythmic amplitudes in Smg6 mutants was highly significant ( Fig. 7K ).

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