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Temporal Trends in the Disease Burden of Colorectal Cancer with Its Risk Factors at the Global and National Level from 1990 to 2019, and Projections Until 2044.

Clin Epidemiol · 2023 · PMC9842526 · PMID 36659904

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an increasing trendno p-value reported
Moreover, ASIR showed an increasing trend from 22.25/100,000 persons (95% UI, 21.29–22.97) in 1990 to 26.71/100,000 persons (95% UI, 24.58–28.89) in 2019, with an average annual rate of 0.58% ( Table 1 ).

also in 63,971 other papers

a decreasing trendno p-value reported
These two regions showed a decreasing trend in age-standardized DALY rates.

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.