ELISA assessment of the serum ITPR2 levels revealed a significantly decrease in rats in the CKD group at 4 weeks and a slightly increasing trend without statistical difference at 16 weeks compared to rats in the sham group ( Figure 7(c) ).
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Inositol 1,4,5-trisphosphate receptor type 2 is associated with the bone-vessel axis in chronic kidney disease-mineral bone disorder.
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