Still, given that tRNAs are involved in decoding mRNA transcript into a protein, it is probable that its induction is linked to the decoding of the transcripts of HSPEI-MOB4 (a conjoined gene 56 composed of heat shock 10 kDa protein 1 (chaperonin 10)) and MOB4 (MOB family member 4, phocein) and HSPA1A (Heat Shock Protein Family A (Hsp70) Member 1A) given their respective second and fifth position in the top five upregulated genes with highly significant fold-increases but only in the engineered cartilage from female hBMSC in response to the ten parabolas of microgravity.
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Transcriptomic response of bioengineered human cartilage to parabolic flight microgravity is sex-dependent.
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