Exosomes derived from MDR cells induce cetuximab resistance in CRC via PI3K/AKT signaling‑mediated Sox2 and PD‑L1 expression.

Exp Ther Med · 2023 · PMC9852420 · PMID 36741914

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an increasing trendno p-value reported

Furthermore, an increasing trend (brown staining indicating positive cells) of serine/threonine-protein kinase BRAF protein expression levels was also identified in patients with mCRC with a lack of response to cetuximab therapy (KRAS mutant group).

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