Methanol extract of <i>Inonotus obliquus</i> improves type 2 diabetes mellitus through modifying intestinal flora.

Compared with the DB group, the mice in the IO group showed a decreasing trend in blood glucose and AUC at each time point, including an evident decrease in blood glucose level at 30 min ( p < 0.01), a remarkable decrease at 120 min ( p < 0.05) and restored basal level ( Figures 1B, C ). 3.3.

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In contrast to the mice in the K group, mice in the DB group had highly significant differences in COG function in J: Translation, ribosomal structure and biogenesis, M: Cell wall/membrane/envelope biogenesis, F: Nucleotide transport and metabolism and N: Cell motility ( p < 0.01).

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