Sensing of SARS-CoV-2 by pDCs and their subsequent production of IFN-I contribute to macrophage-induced cytokine storm during COVID-19.

Sci Immunol · 2022 · PMC9853436 · PMID 36083891

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highly significantno p-value reported

Similarly to our BAL data, macrophages in lungs had highly significant positive correlation between the presence of IFN-induced signaling and the expression of proinflammatory cytokines in macrophages ( Fig. 1I ).

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