Cerebellar granule neurons induce Cyclin D1 before the onset of motor symptoms in Huntington's disease mice.

Acta Neuropathol Commun · 2023 · PMC9854201 · PMID 36670467

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Comparison of our cell type-specific data with bulk RNAseq of striata from the zQ175DN HD knock-in model [ 10 ] showed a highly significant overlap between gene expression changes detected in cerebral Gad2 + samples and bulk striatal tissue at all observed time points (Fig.

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