Lactate-Mediated Signaling in the Brain-An Update.

Brain Sci · 2022 · PMC9856103 · PMID 36672031

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highly significantno p-value reported

In a luminescence assay, the application of Lac within the range of concentrations which we consider physiological (less than 5 mM) to HEK cells expressing GPR137 resulted in highly significant increases in cAMP. 5 mM of Lac elevated luminescence to ~175% relative to control.

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