Role of HIPEC after Complete Cytoreductive Surgery (CRS) in Peritoneal Recurrence of Platinum-Sensitive Recurrent Ovarian Cancer (OC): The Aim for Standardization at Two Reference Centers for CRS.

In univariate analyses of overall survival according to the treatment factors, 90 min HIPEC (HR 0.541, 95%-CI 0.300–0.978; p = 0.042) and treatment with cisplatin only (as opposed to cisplatin and doxorubicin, which yielded an HR of 2.269 95%-CI 1.230–4.186; p = 0.009) appeared to be significantly superior in terms of overall survival, whereas only a small trend was observed for CCR with a benefit of CC0 resected patients ( Figure 4 , Table 4 ).

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