When evaluating the entire study period, the highest prevalence of use in pediatric patients was observed in Group J, albeit with a decreasing trend (with the proportion of patients with at least one prescription in a year ranging from 63.0% in 2008 to 48.2% in 2018), followed by Group A, showing an increasing trend (range from 12.9% in 2008 to 23.4% in 2018, with a maximum of 25.3% in 2016).
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Profile of Drug Utilization in Patients with Rare Diseases in Tuscany, Italy: A Population-Based Study.
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