Elevation of cell-associated HIV-1 transcripts in CSF CD4+ T cells, despite effective antiretroviral therapy, is linked to brain injury.

Proc Natl Acad Sci U S A · 2022 · PMC9860316 · PMID 36413502

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closest p · 0.1× alpha

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highly significantP = 0.003actually significant

Importantly, there was a highly significant correlation between HIV-1 CA-RNA transcription in CSF cells and HIV-1 CA-RNA transcription in CD4+ T cells from PBMCs ( Fig. 1 H ; r = 0.83; P = 0.003).

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