Digital twin demonstrates significance of biomechanical growth control in liver regeneration after partial hepatectomy.

An intensity-based OTSU segmentation identified the shape of the lobe which was assumed to represent the position of the Glisson capsule ( Figure 2 C, red) that generally encapsulates the whole lobe: In a mathematical model on the scale of a lobe, the mechanical impact of the Glisson capsule (E(Capsule) ≈ 400 kPa, ( Carter et al., 2000 )) may be significant and thus must be taken into account.

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