Interaction between <i>SIDT2</i> and <i>ABCA1</i> Variants with Nutrients on HDL-c Levels in Mexican Adults.

Nutrients · 2023 · PMC9861312 · PMID 36678241

Europe PMC DOI

hedged sentences

0.0640

closest p · 1.3× alpha

0.0640

boldest claim

The sentences

a marginal trendp = 0.064so close (0.05 < p ≤ 0.1)

Even though our analysis did not reveal a significant effect of the rs17120425 x rs9282541 interaction, we observed a marginal trend (β = 0.12, p = 0.064).

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marginal significanceno p-value reported

However, the rs17120425 x rs9282541 analysis interaction showed a marginal significance for the HDL-c levels under categorical (Slope difference = 0.51, p interaction = 0.03) (data not shown) and continuous (slope difference= 0.064, p interaction = 0.064) analysis ( Figure 1 b).

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may be significantno p-value reported

Therefore, the effect of this interaction may be significant in people with an increased risk of CVD and could represent a potential therapeutic strategy against dyslipidemia.

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borderline significantno p-value reported

The rs17120425-A and rs9282541-A alleles were borderline significant for the male group ( Table S2 ). 3.3.

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