Neuroprotective effect of astragalin via activating PI3K/Akt-mTOR-mediated autophagy on APP/PS1 mice.

Cell Death Discov · 2023 · PMC9867706 · PMID 36681681

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an increasing trendno p-value reported

In our in vitro and in vivo results, the protein of LAMP-1 was in an increasing trend after AST was applied on APP/PS1 mice and Aβ25-35-exposed HT22 cells, indicating that AST may promote the fusion of autophagosomes and lysosomes by enhancing LAMP-1 levels.

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