Alterations of plasma exosomal proteins and motabolies are associated with the progression of castration-resistant prostate cancer.

J Transl Med · 2023 · PMC9867857 · PMID 36681849

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highly significantno p-value reported

Consistently, P < 0.01 (**), P < 0.001 (***), and P < 0.0001 (****) indicated highly significant findings.

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a decreasing trendno p-value reported

The metabolites in the PCa samples showed a decreasing trend in most cases, and only 2-(2-Methylbutanoyl)-9-(3-methyl-2E-pentenoyl)-2b,9a-dihydroxy-4Z,10(14)-oplopadien-3-one and acetylglycine showed levels 2.01- and 1.48-fold higher than those in the TFC group.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.