Computationally profiling peptide:MHC recognition by T-cell receptors and T-cell receptor-mimetic antibodies.

Front Immunol · 2022 · PMC9868621 · PMID 36700202

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a notable trendno p-value reported

Additionally, a notable trend in recent years has been to solve TCR:pMHC complexes that ‘break the rules’ rather than adhere to them ( 48 ), which may interfere with interpretability of the properties of our ‘representative TCRs’ as reflective of typical TCR behavior.

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